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H651

American Staffordshire Terrier Juvenile Laryngeal Paralysis and Polyneuropathy (ALPP) is a severe neurological disorder characterized by difficulty breathing and loss of muscle coordination.

25 días laborables

Especificaciones

Breeds

Gene

Organ

specimen

Hisopo, sangre EDTA, sangre Heparina, Semen, Tejido

Mode of Inheritance

Also known as

Información específica de la prueba

American Staffordshire Terrier Juvenile Laryngeal Paralysis and Polyneuropathy (ALPP) is a severe neurological disorder characterized by difficulty breathing and loss of muscle coordination. This variant, observed in the American Staffordshire Terrier, is caused by an autosomal recessive genetic mutation.

Características clínicas

Affected dogs typically present around 3 months of age with laryngeal paralysis and respiratory distress. Loss of movement coordination often develops a few months to a few years later. Additional symptoms may include limb weakness, ataxia (loss of coordination), progressive muscle atrophy, altered barking (dysphonia), vomiting, and swallowing difficulties. In some cases, symptoms may stabilize, although episodes of ataxia and swallowing difficulties may persist. The dogs of which symptoms stabilize, seem to lead an almost normal life.

Información adicional

Esta prueba es realizada por un laboratorio externo. CombiBreed se encarga de la mediación entre usted como cliente y el laboratorio externo. En este caso, CombiBreed no se hace responsable del comportamiento del cliente y/o contratista.

Referencias

Pubmed ID: Unpublished data University of Missouri

Omia ID: 1970

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